Coupons are a great way to save money, but not all cashiers are informed of a store's coupon policy. Be sure you read and know your favorite stores' policies and I recommend even printing a copy to keep in your coupon carrier/binder just in case an issue arises.
Here are links to WNY area stores that accept manufacturer's coupons:
Market in the Square
Rite Aid Pharmacy
Tops Friendly Markets